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Gene Lists

Our gene lists are pathogenesis-based transcripts sets (PBTs) that were generated by using Affymetrix Microarrays. The PBTs were defined to represent the major biologic events in cellular graft rejection, cytotoxic T-cell infiltration, interferon-gamma effects and epithelial deterioration. They were derived from experimental mouse kidney transplants, cultured cells and human kidney biopsies.

References:
The Molecular Phenotype of Kidney Transplants. PF Halloran, DG de Freitas, G Einecke, KS Famulski, LG Hidalgo, M Mengel, J Reeve, J Sellares and B Sis. American Journal of Transplantation 2010;10:2215-2222

​Fundamental Concepts Regarding Graft Injury and Regeneration: Tissue Injury, Tissue Quality, and Recipient Factors. C Kreepala, KS Famulski and PF Halloran. Textbook of Organ Transplantation, First Edition. Edited by AD Kirk, SJ Knectle, CP Larsen, TC Pearson and JC Madsen. © 2013 John Wiley & Sons, Ltd. Published 2013 by John Wiley & Sons, Ltd., Chapter 10, pp 99-118
  

Human PBTs: kidney and inflammatory cells; HG U133_2.0_plus arrays 

Core PBT List                                                                      Core PBTs.xlsCore ​PBTs.​xls

 

Human PBTs: cardiac injury and cardiac associated; HG U133_2.0_plus arrays 

​Cardiac injury and cardiac associated transcripts cIRIT.xlsxcIRIT HT.xlsx
   

Mouse PBTs; MG 430_2.0 arrays

CTL associated transcripts mCATs.xlsmCATs.xls
True gamma IFN and rejection induced transcripts mtGRITs.xlsmtGRITs.xls
​Occult gamma IFN and rejection induced transcripts moGRITs.xlsmoGRITs.xls
​Gamma-IFN suppressed transcripts mGSTs.xlsmGSTs.xls
​Alternative Macrophage Activation Transcripts mAMATs.xlsmAMATs.xls
​Class I-suppressed transcripts mCISTs.xlsmCISTs.xls
​Injury and repair induced transcripts mIRITs.xlsmIRITs.xls
​Renal transcripts mRTs.xlsmRTs.xls
​Solute Carriers mSlcs.xlsmSlcs.xls